Home > diabete, Medicina > Come funziona il diabete

Come funziona il diabete

Il diabete è una malattia strana. Esiste in tante forme, le cause scatenanti sono tutt’ora semisconosciute, e nella stragrande maggioranza dei casi è cronica.. una volta che te la becchi è per tutta una vita.

Della serie “Un diabete è per sempre”.

Di seguito tenterò di spiegare a grandi linee cosa è il diabete e come funziona. Chi sa l’inglese, può anche risparmiarsi questo supplizio ed andare a vedere direttamente al sito How Diabetes Works, in cui viene spiegato molto meglio. Winking.

Piccola Introduzione – Metabolismo degli zuccheri

Il nostro corpo utilizza il glucosio, una molecola molto semplice di zucchero, come principale carburante per le attività delle cellule.Queste attività includono la produzione di proteine, grassi, aminoacidi. Le cellule nervose sono le uniche che lo utilizzando direttamente. Il glucosio quindi, rappresenta la principale fonte di energia per il nostro corpo. No glucosio, No party.

 

Il glucosio si ricava da ciò che mangiamo comunemente – non solo dolci quindi – come risultato della digestione. Esiste tutto un meccanismo di autoregolamentazione del livello di glucosio nel sangue ottenuto grazie a due ormoni, l’insulina ed il glucagone. Entrambi gli ormoni vengono prodotti da un gruppetto di cellule localizzati in aree particolari del pancreas (dette Isole di Lengerhans), denominate rispettivamente cellule beta e cellule alfa.

 

 

 

 

In particolare i due ormoni hanno azioni opposte:

  • L’insulina si occupa di smistare il glucosio nelle cellule o stimolare la sua trasformazione in glicogeno, una specie di riserva di carburante da poter usare in seguito. Il suo effetto è quello di abbassare il livello di glucosio nel sangue (detto anche glicemia).
  • Il glucagone invece stimola la conversione del glicogeno in glucosio, con l’effetto opposto di alzare la glicemia.

 

 

 

Se tutto va bene, la glicemia rimane all’incirca costante, tranne dei picchi in prossimità dei pasti. Più o meno come un termostato di una caldaia e che regola quando accenderla o spegnerla per mantenere costante la temperatura nella vostra casetta.Big Grin

Se funziona… ma anche no!

Diabete e le varie forme della sfiga

La prima legge di Murphy recita:

Se qualcosa può andare storto, stai sicuro che lo farà

Il diabete fondamentalmente si ha quando qualcosa nel metabolismo degli zuccheri si inceppa. E siccome le cose possono andare storte in molti modi, ecco che ci sono varie forme di diabete:

  1. Diabete tipo1, detto anche diabete mellito, diabete giovanile o insulinodipendente. I “fortunati” appartenenti a questa categoria non riescono più a produrre insulina. Ciò in genere è dovuto ad una reazione autoimmune… il sistema immunitario, oltre a combattere i virus, pensa bene di prendere a mazzate le cellule beta – nemmeno fossero dei manifestanti al G8 – e ne causano la distruzione. I diabetici di tipo 1 sono circa il 10% del totale dei diabetici ed in genere sono giovani sotto i 40 anni.
  2. Diabete tipo 2, detto non-insulinodipendente o diabete senile. Al contrario del tipo1 i tipo2 possono produrre insulina ma questa agisce male (insulinoresistenza). Questo tipo di diabete è il più diffuso in assoluto, raggiungendo circa l’85% della popolazione diabetica, per lo più over 50. Nonostante tutto è in seconda posizione in lista, tiè!
  3. Diabete gestazionale. Questo può colpire le donne in gravidanza, in quanto alcuni ormoni prodotti in questo periodo hanno un effetto contrario all’insulina. Alla fine, è un diabete “temporaneo” in quanto nella maggioranza dei casi va via con la nascita del bambino (…ma anche no :()

Ecco un video che spiega bene (in inglese).

Sintomi

Le varie forme di diabete hanno origini diverse e vengono trattate in maniera differente ma vengono considerate come la stessa patologia. La ragione è “di comodo”, cioè hanno tutte gli stessi sintomi:

  1. Perdita improvvisa di peso
  2. Sete eccessiva ed aumento di fame
  3. Si fa pipì spesso
  4. Affaticamento
  5. Difficoltà a rimarginare le ferite
  6. Diminuzione improvviso della vista
  7. Presenza di glucosio nelle urine

Sono sintomi che spesso vengono sottovalutati dai medici di base, o alpiù considerati come indice di depressione o legati semplicemente alla crescita (specie nella popolazione giovanile)… è purtroppo ancora frequente che casi di diabete vengano diagnosticati in ritardo, quando ormai i danni li hanno fatti…

I sintomi sono facilmente spiegabili se si considera che un diabetico ha una ridotta (o nulla) capacità di usare l’insulina. Cosa succede in questo caso? L’insulina non fa il suo lavoro, che è quello di far passare il glucosio nelle cellule oppure di immagazzinarlo nel fegato.. rimane quindi a circolare nel sangue. Si ha quindi un aumento di glicemia.

Le cellule però non ricevendo carburante muoiono di fame, per cui usano le scorte e stimolano il fegato per rilasciare il glicogeno. Risultato? La glicemia aumenta ancora, si perde peso ed aumenta la fame… Sembra una scena da girone dantesco, uno mangia ma nonostante tutto aumenta la fame e dimagrisce notevolmente.

Nel frattempo il glucosio inizia ad intasare il sangue, che diventa più denso. Da qui la difficoltà a rimarginare le ferite, e problemi agli organi periferici (occhi soprattutto). Il glucosio in eccesso viene automaticamente filtrato dai reni nelle urine, stimolando la sete e le frequenti visite al bagno.

Video a riguardo: Sintomi

E’ importante intervenire il prima possibile, più si aspetta più è probabile che scattino le complicanze.

Annunci
  1. 12 febbraio 2013 alle 14:01

    Every weekend i used to pay a visit this site, because i wish for enjoyment, as this
    this site conations in fact pleasant funny material too.

  2. 27 febbraio 2013 alle 22:39

    Unquestionably imagine that that you said. Your favorite justification appeared to be on the net the simplest factor to be mindful of.
    I say to you, I definitely get annoyed at the same
    time as other people think about concerns that they plainly don’t know about. You controlled to hit the nail upon the highest and also outlined out the whole thing with no need side-effects , people can take a signal. Will probably be back to get more. Thanks

  3. 25 aprile 2013 alle 15:30

    Find out the name of the certifier and look up the standards online if
    you are unsure. Concentrating on a diet of LOTS of fruits and vegetables
    (preferably uncooked) and no junk food, should give you an observable improvement within 30
    days. It is said to aid in digestion, reduces doggy odor and bad breath.

  4. 29 aprile 2013 alle 05:08

    It tightens skin, especially, around the nose controlling
    the enlargement of aged pores. As a skin protectant, sesame
    oil attracts oil soluble toxins to the surface which can then be
    washed off with mild soap and water. However it is used in breads,
    biscuits and cakes, as then it does not get direct heat.

  5. 11 maggio 2013 alle 04:43

    Let’s have a look at few of the things which will help you. If, you are from one of those who think the higher megapixel camera is best then you are surely mistaken. There are more important things to consider when deciding if you will pay more for a camera.

  6. 12 maggio 2013 alle 10:06

    You can pick up basic equipment for very little or you can go for
    higher quality tackle and spend hundreds or thousands.
    Pay close attention to the mayflies, midges, and stoneflies in the area and try to
    match your flies to the size and type fish are
    biting on. All the equipment is included in your deep sea fishing charter Cancun and the boat is so nice you will want to take advantage of the luxury fishing
    afforded from the Querida del Mar.

  7. 12 maggio 2013 alle 12:59

    What you want to discuss and how you discuss various
    issues is left to you, which again is an advantage especially if you are creating an online talk radio station.
    There are hundreds of people working in foreign aid missions, expats, Peace Corps, and others in relief
    and business sectors. With 75 plus musical channels on the bandwidth,
    you cannot stay out of music in any point of time.

  8. 12 maggio 2013 alle 12:59

    Ahaa, its good conversation concerning this article here at this website, I have read all
    that, so now me also commenting at this place.

  9. 12 maggio 2013 alle 15:27

    For many regions, the entire rpm distributed free of charge STB The costs have been overwhelmed, and then implementation of the Reconstruction of two-way network, the funding is clearly beyond its capability.
    There are hundreds of people working in foreign aid missions, expats, Peace Corps,
    and others in relief and business sectors. Turn on iheartradio and then look at a different app,
    your station will keep playing and you can control everything from the “running apps” menu (double-click the home
    button).

  10. 13 maggio 2013 alle 07:12

    Try simple games and check how your internet connection is and then move on
    play more games. However, every character in the game (even supporting
    players) should be presented in this same detail.
    In this addictive puzzle game, catch that damn fly and
    avoid those tricky obstacles.

  11. 14 maggio 2013 alle 07:48

    clients, Rachel, who got back together with her ex. The only downside
    of it in a lot of people’s eyes is the fact that there is no multiplayer content. In this addictive puzzle game, catch that damn fly and avoid those tricky obstacles.

  12. 14 maggio 2013 alle 11:20

    Much like Safari, the Camera app, the App Store and i – Pod, Game
    Center has no option to be deleted when editing your apps. At the same time, web games
    seemed like the future of gaming, and we wanted to be a part of it.

    In this addictive puzzle game, catch that damn fly and avoid those
    tricky obstacles.

  13. 15 maggio 2013 alle 19:12

    I am sure this post has touched all the internet people, its really really fastidious post on building up new webpage.

  14. 16 maggio 2013 alle 15:24

    An impressive share! I have just forwarded this onto a coworker who has been
    conducting a little research on this. And he actually ordered me breakfast because I stumbled upon
    it for him… lol. So let me reword this…. Thank YOU for
    the meal!! But yeah, thanks for spending some time to talk about this issue here on your website.

  15. 16 maggio 2013 alle 19:28

    What a material of un-ambiguity and preserveness of valuable knowledge regarding unpredicted feelings.

  16. 17 maggio 2013 alle 03:11

    Broadcast satellite “in the Star on the 9th,” was successfully launched in
    June last year, it can be said is a milestone in the field of live satellite event.

    This means that everyone in the whole wide world can access this new kind of radio and you are assured that the programs as well as the list of radio stations you are listening to are all automatically updated.

    Another radio commercial production tip to chew on is to make sure the audio quality is excellent on any
    spot your produce.

  17. 18 maggio 2013 alle 10:31

    Really no matter if someone doesn’t know after that its up to other visitors that they will help, so here it takes place.

  18. 26 maggio 2013 alle 05:01

    In fact, therapeutic relief can be achieved simply by putting aromatherapy oils
    on your body, with one particularly famous oil for this purpose being rosehip oil.

    It is an effective balm for flare-ups of acne,
    too. It contains vitamins A, E, and other essential nutrients including omega-3 and omega-6 fatty acids.

  19. 27 maggio 2013 alle 23:24

    Amazing article. I appreciate you for sharing
    it to us. I have learned very much.

  20. 28 maggio 2013 alle 05:01

    The oil is effective in preventing sun burns and is used in sunscreen lotions.
    In addition it promotes the healing of the skin by its astringent and antiseptic qualities.
    It is not an easy job to extract the oil from the grape seeds, since they are tiny
    with a hard shell.

  21. 10 giugno 2013 alle 15:45

    This is very interesting, You’re a very professional blogger. I’ve joined
    your feed and sit up for searching for extra of your wonderful post.

    Additionally, I have shared your web site in my social networks

  22. 13 luglio 2013 alle 18:11

    Hey I am so delighted I found your blog page, I really
    found you by mistake, while I was browsing on Digg for something else, Anyways I am here now and
    would just like to say thanks a lot for a incredible post and a
    all round entertaining blog (I also love the theme/design), I don’t have time to go through it all at the moment but I have saved it and also added your RSS feeds, so when I have time I will be back to read much more, Please do keep up the fantastic job.

  23. 16 luglio 2013 alle 07:52

    I believe that is one of the such a lot significant information for me.
    And i am happy studying your article. However wanna statement on few common issues, The website style is perfect, the articles
    is in point of fact great : D. Excellent job, cheers

  24. 23 luglio 2013 alle 15:02

    Thanks for the tips you have provided here. Cheers!

  25. 23 luglio 2013 alle 18:28

    I just couldn’t depart your site because I very enjoyed the standard information an individual provide for your
    visitors? Is going to be back often in order to check new posts

  26. 26 luglio 2013 alle 16:57

    you are in point of fact a excellent webmaster. The site loading speed
    is amazing. It kind of feels that you are doing any unique trick.
    Furthermore, The contents are masterpiece. you’ve done a excellent activity in this matter!

  27. 17 ottobre 2013 alle 13:35

    I am really loving the theme/design of yur weblog.
    Do you ever run into any internet browser compatibility
    problems? A couple of my blog visitors have complained about
    my website not operating correctly in Explorer but looks greast iin Opera.
    Do you have any advice to help fix this problem?

  28. 27 ottobre 2013 alle 19:33

    Unquestionably believe that which you said. Your favourite justification appeared to
    be on the web the easiest factor to bear in mind of.
    I say to you, I definitely get annoyed whilst folks think about worries that they just do not recognise about.
    You managed to hit the nail upon the highest and defined out the entire thing with no need side-effects , folks could take
    a signal. Will probably be back to get more. Thank you

  29. 1 novembre 2013 alle 06:02

    Amazing issues here. I am very glad to see your article. Thank you so much and I am taking a look ahead to touch you.

    Will you kindly drop me a mail?

  30. RaredrydayBed
    28 novembre 2013 alle 05:57

    [url=http://www.theinnatmtview.com/webstore/index.html][b]michael kors handbags outlet[/b][/url]However, many parents and teachers think that websites will affect their learning. Because students must spend time to learn more about manage websites,on those grounds that a lot fewer just how long learning[url=http://www.theinnatmtview.com/webstore/index.html][b]michael kors outlet store[/b][/url]See this i am going to really do not think that material and designing usually ach invaluable Meet all of our should is king. Our market is this : an all in one extra – large market everywhere in the the ladies.Care a great deal more about our are going to want.[url=http://www.theinnatmtview.com/webstore/index.html][b]michael kors outlet online[/b][/url]the daytime i always agree which i do nothing more than tought including all of our friendship,maybe i usually in the event that never ever lend her that much in the way money, and say that i don’t have that much in the way money.do nothing more than lend her 100 or200rmb.[url=http://www.10thavenuetheatre.com][b]michael kors outlet[/b][/url]you the lessons all your family are going to want to learn.[url=http://www.theinnatmtview.com/webstore/index.html][b]michael kors outlet[/b][/url]

  31. 29 dicembre 2013 alle 16:46

    I’m really enjoying the theme/design of your weblog. Do you ever run
    into any internet browser compatibility problems? A few of my blog readers have complained about my website not working correctly in Explorer but
    looks great in Opera. Do you have any ideas to help fix this
    problem?

  32. 17 gennaio 2014 alle 12:23

    Very shortly this site will be famous amid all blogging
    and site-building users, due to it’s nice content

  33. 7 marzo 2014 alle 06:58

    Hello! Do you know if they make any plugins to help with Search Engine Optimization?

    I’m trying to get my blog to rank for some targeted keywords but I’m
    not seeing very good results. If you know of
    any please share. Thank you!

  34. 11 marzo 2014 alle 02:04

    Excellent goods from you, man. I’ve understand your stuff previous to
    and you are just too fantastic. I really like
    what you’ve acquired here, really like what you are stating and the way iin which you
    say it. You make it entertaining and you still cre for to keep it smart.
    I can’t wait to read much more fom you. This is actually a great
    site.

  35. 11 marzo 2014 alle 23:28

    Hi there I am so delighted I found your webpage, I really found you by accident, while I was searching on
    Digg for something else, Anyways I am here now and would just like to say thanks a lot for a marvelous post and a all round enjoyable blog
    (I also love the theme/design), I don’t have time to
    go through it all at the moment but I have saved it and also added your RSS feeds,
    so when I have time I will be back to read more, Please do keep up the fantastic b.

  36. 13 marzo 2014 alle 16:00

    Asking questions are in fact fastidious thing if you are not understanding anything entirely, except this paragraph gives nice understanding yet.

  37. 14 marzo 2014 alle 23:30

    I think this is among the most significant info for me.
    And i am glad reading your article. But should remark on few general things, The site style is perfect,
    the articles is really excellent : D. Good job,
    cheers

  38. 27 marzo 2014 alle 15:40

    I simply could not leave your website prior to suggesting that I extremely
    enjoyed the standard information an individual supply to your
    visitors? Is going to be back frequently in order to investigate cross-check new posts

  39. 30 marzo 2014 alle 14:44

    Thanks to my father who stated tto me cocerning this blog, this blog
    is actually awesome.

  40. 2 aprile 2014 alle 15:09

    Woah! I’m really digging the template/theme of this blog.
    It’s simple, yet effective. A lot of times it’s tough to get that “perfect balance” between usability and visual appeal.
    I must say you have done a great job with this. Additionally, the
    blog loads extremely fast for me on Opera. Exceptional Blog!

  41. 5 aprile 2014 alle 22:16

    It’s enormous that you are getting ideas from this post as well as from our
    discussion made here.

  42. 10 aprile 2014 alle 20:13

    Helpful information. Fortunate me I discovered your website by chance, and I am shocked why this twist
    of fate didn’t came about earlier! I bookmarked it.

  43. 14 aprile 2014 alle 23:46

    Hurrah, that’s what I was searching for, what a material!
    existing here at this web site, thanks admin of this web site.

  44. 15 aprile 2014 alle 01:49

    Hi there! Someone in my Myspace group shared this site with
    us so I came to check it out. I’m definitely enjoying the information.
    I’m book-marking and will be tweeting this to my followers!
    Wonderful blog and terrific design and style.

  45. 19 aprile 2014 alle 14:17

    You could definitely see your expertise within the work you write.
    The world hopes for even more passionate writers like
    you who aren’t afraid to mention how they believe. Always go after your heart.

  46. 20 aprile 2014 alle 04:10

    Hello, I think your site might be having browser compatibility issues.
    When I look at your blog in Firefox, it looks fine but when opening in
    Internet Explorer, it has some overlapping. I just wanted to give you a quick heads up!
    Other then that, fantastic blog!

  47. 20 aprile 2014 alle 11:04

    You are so cool! I don’t suppose I’ve read through something like that before.
    So great to find somebody with genuine thoughts
    on this issue. Seriously.. thanks for starting
    this up. This web site is something that is needed on the internet, someone with a little originality!

  48. 30 aprile 2014 alle 20:33

    Very soon this site will be famous amid all blog people,
    due to it’s good articles or reviews

  49. 2 maggio 2014 alle 20:16

    I’m more than happy to uncover this great site. I wanted to thank you for your time just for this wonderful read!!
    I definitely really liked every little bit of it and I have you book-marked to look at new information
    in your site.

  50. 4 maggio 2014 alle 00:22

    It’s amazing in support of me to have a web page, which is beneficial for my experience.

    thanks admin

  51. 5 maggio 2014 alle 15:24

    Fantastic goods from you, man. I have understand your stuff previous to and you’re just extremely fantastic.

    I actually like what you’ve acquired here, certainly like what you are stating and the way in
    which you say it. You make it enjoyable and you still care for to keep it sensible.
    I can not wait to read much more from you. This is really a tremendous web site.

  52. 6 maggio 2014 alle 06:59

    Aw, this was a really good post. Taking a few minutes and actual effort to generate a really good article…
    but what can I say… I procrastinate a lot and never manage to get nearly anything done.

  53. 6 maggio 2014 alle 21:40

    Do you have any video of that? I’d like to find out more details.

  54. 7 maggio 2014 alle 04:15

    Good day! I could have sworn I’ve been to this blog before but after cheecking through sone
    of the post I realized it’s new to me. Anyhow, I’m definitely happy
    I found it and I’ll be bookmarking and checking back often!

  55. 7 maggio 2014 alle 19:55

    Its not my first time to pay a visit this web site, i am visiting this website dailly
    and obtain nice facts from here every day.

  56. 7 maggio 2014 alle 19:57

    I am curious to find out what blog platform you’re utilizing?
    I’m having some minor security problems with my latest website and I’d
    like to find something more secure. Do you have any recommendations?

  57. 22 maggio 2014 alle 07:12

    Thank you for any other magnificent post. The place else could anyone get that type of information in such an ideal approach of writing?
    I have a presentation subsequent week, and I’m on the look for such
    info.

  58. 22 maggio 2014 alle 21:38

    Hi, every time i used to check weblog posts here in the early hours in the morning, as i enjoy to
    gain knowledge of more and more.

  59. 30 maggio 2014 alle 01:09

    I’m truly enjoying the design and layout of your site.It’s a very easy on the eyes which makes it much more enjoyable for me to come here and visit more often. Did you hire out a designer to create your theme? Excellent work!Check out my blog post Télécharger Deer Hunter 2014 (gratuit)

  60. 3 giugno 2014 alle 17:11

    WOW just what I was searching for. Came here by searching for weight training

  61. 4 giugno 2014 alle 01:42

    Unquestionably consider that that you stated. Your
    favorite justification seemed to be on the web the easiest factor to remember of.
    I say to you, I definitely get annoyed while
    other folks consider issues that they just do
    not recognize about. You controlled to hit the nail upon the top and defined out the whole thing without
    having side effect , other folks could take a signal. Will probably be back
    to get more. Thank you

  62. 6 giugno 2014 alle 15:19

    Terrific work! That is the kind of information that
    are meant to be shared across the internet. Shame on Google for now not positioning this submit higher!
    Come on over and visit my web site . Thank you
    =)

  63. 10 giugno 2014 alle 13:08

    At this time it sounds like BlogEngine is the best blogging
    platform out there right now. (from what I’ve read) Is that what you are using on your blog?

  64. 15 giugno 2014 alle 01:56

    It’s hard to find knowledgeable people on this topic, however, you sound like you know what
    you’re talking about! Thanks

  65. 17 giugno 2014 alle 20:04

    Search engine optimization (SEO) is a method designed to improve the flow of organic visitors to
    a website by achieving a higher ranking within search engine result pages (SERPs).
    Google – Preview – A simple tool, does just as its name says.

    Perhaps it’s better not be using these social networks, they
    say they keep people connected, but only in a virtual
    world, it probably prevents a lot of people from
    going outside and really connecting.

  66. 18 giugno 2014 alle 02:21

    Hmm is anyone else experiencing problems with the pictures on this blog loading?
    I’m trying to find out if its a problem on my end or
    if it’s the blog. Any suggestions would be greatly appreciated.

  67. 19 giugno 2014 alle 09:45

    I am truly delighted to glance at this blog posts which includes plenty
    of helpful data, thanks for providing these kinds of information.

  68. 23 giugno 2014 alle 09:38

    Such are the ingredients of Adiphene that its one finest selling level is the shortage of
    dangerous uncomfortable side effects. Adiphene the new weight loss formula is now
    available with the power of 11 different fat burners to boost weight loss.
    Having said that, the study has shown that just about anything that can maximize the metabolism,
    also can raise the weight reduction even if the human being is just resting.

  69. 27 giugno 2014 alle 18:36

    Don’t let fat cost-free or perhaps gentle meals trick
    anyone; them usually comprise copious amounts connected with one more unhealthy element.
    The huge distinction between Adiphene and Adipex is that
    Adiphene is a product that uses a sequence of natural
    and secure to use ingredients. Assuming that you aren’t a super-taught individual, you will
    have some major snags adding on control over your zealous urges towards consuming distinctive sustenances.

  70. 28 giugno 2014 alle 10:12

    This paragraph is actually a nice one it helps new the web viewers, who are
    wishing in favor of blogging.

  71. 28 giugno 2014 alle 10:15

    It’s remarkable for me to have a web page, which is good for my knowledge.
    thanks admin

  72. 2 luglio 2014 alle 08:28

    I recently much like the helpful information you present to your articles or blog posts. Let me bookmark ones weblog plus have a look at yet again in this article often. Now i’m slightly certain I am going to find out plenty of brand-new goods appropriate below! Have fun for the!

  73. 2 luglio 2014 alle 12:46

    Howdy are using WordPress for your blog platform? I’m new to the
    blog world but I’m trying to get started and create my own. Do you need any html coding
    expertise to make your own blog? Any help would be greatly appreciated!

  74. 4 luglio 2014 alle 02:09

    Does your website have a contact page? I’m having trouble
    locating it but, I’d like to shoot you an email. I’ve
    got some recommendations for your blog you might be interested in hearing.
    Either way, great website and I look forward to seeing it
    improve over time.

  75. 6 luglio 2014 alle 01:28

    It’s a shame you don’t have a donate button! I’d
    certainly donate to this excellent blog! I guess for now i’ll settle for book-marking and adding your RSS feed to my Google account.

    I look forward to fresh updates and will share this site with my Facebook group.
    Talk soon!

  76. 8 luglio 2014 alle 01:45

    Its such as you read my mind! You appear to understand so much approximately this,
    such as you wrote the e-book in it or something. I believe
    that you could do with some percent to power the message house a little bit, however instead of that,
    this is wonderful blog. A fantastic read. I’ll definitely be back.

  77. 10 luglio 2014 alle 00:25

    Thanks for finally talking about >Come funziona il diabete |
    La Strana Malattia <Liked it!

  78. 10 luglio 2014 alle 11:16

    Please let me know if you’re looking for a article writer for your site.
    You have some really great posts and I feel I would be a good asset.
    If you ever want to take some of the load off, I’d love
    to write some content for your blog in exchange for a link back to mine.

    Please shoot me an e-mail if interested. Thanks!

  79. 10 luglio 2014 alle 20:38

    A Daisy Girl Scout, yahoo 5 ways to wear a scarf she enjoyed musical theater.
    There was a hhuge loss. He has published wieely on the
    topic of office management and a secure set of capabilities in clerical work.

  80. 12 luglio 2014 alle 10:57

    I enjoy, result in I found exactly what I used to be having a look for.

    You’ve ended my 4 day long hunt! God Bless you man. Have a
    great day. Bye

  81. 14 luglio 2014 alle 19:45

    What’s up i am kavin, its my first occasion to commenting anyplace,
    when i read this article i thought i could also create comment due
    to this brilliant paragraph.

  82. 15 luglio 2014 alle 07:10

    Howdy! I simply wish to offer you a huge thumbs up for the great information you have
    got here on this post. I will be returning to your site for more soon.

  83. 16 luglio 2014 alle 09:59

    Hi, You’ve got conducted a fantastic job. I’m going to absolutely bing them and in our check out would suggest to friends and neighbors. I am sure they’ll be taken advantage of this web site.

  84. 18 luglio 2014 alle 18:57

    whoah this blog is magnificent i love studying your posts.

    Stay up the great work! You know, lots of persons are searching round for this info, you could help them greatly.

  85. 18 luglio 2014 alle 21:06

    Woah! I’m really loving the template/theme of this website.
    It’s simple, yet effective. A lot of times it’s
    very difficult to get that “perfect balance” between user friendliness and visual appearance.
    I must say that you’ve deliver a very good job with this.
    In addition, the blog loads very quick for me on Opera. Exceptional Blog!

  86. 24 luglio 2014 alle 01:58

    May I just say what a relief to uncover someone who genuinely
    knows what they’re discussing on the web. You actually know how
    to bring a problem to light and make it important.
    A lot more people need to look at this and understand this side of
    the story. I was surprised you’re not more popular because you most certainly have
    the gift.

  87. 28 luglio 2014 alle 04:33

    I’m amazed, I have to admit. Seldom do I encounter a blog that’s both equally educative and engaging, and without a doubt,
    you’ve hit the nail on the head. The problem is
    something that not enough people are speaking intelligently
    about. I am veery happy I found this during my search for something reating to this.

  88. 28 luglio 2014 alle 17:04

    Quality content is the main to attract the people to pay a visit the website, that’s what this website is providing.

  89. 30 luglio 2014 alle 23:53

    I like what you guys are up too. Such clever work and coverage!
    Keep up the amazing works guys I’ve incorporated you guys to our blogroll.

  90. 4 agosto 2014 alle 07:40

    howdy! , I love a person’s producing quite a great deal! write about most people converse more concerning your publish in AOL? We call for a specialist with this property to fix my own challenge. Maybe that is certainly anyone! Looking in advance to see you actually.

  91. 6 agosto 2014 alle 12:57

    It’s perfect time to make some plans for the future and it is
    time to be happy. I’ve read this post and if I could I wish to suggest you few interesting things or advice.
    Maybe you could write next articles referring to this
    article. I desire to read even more things about it!

  92. 11 agosto 2014 alle 08:22

    What’s up, just wanted to say, I loved this article. It was funny.

    Keep on posting!

  93. 13 agosto 2014 alle 11:29

    Awesome site you have here but I was curious if you knew of
    any forums that cover the same topics talked
    about here? I’d really love to be a part of online community where I can get comments from other knowledgeable individuals that share the same interest.
    If you have any suggestions, please let me know. Cheers!

  94. 14 agosto 2014 alle 07:38

    This site certainly has all the information and facts I needed about this subject and didn’t know who to ask.

  95. 16 agosto 2014 alle 06:48

    I’ve been surfing on-line a lot more than Three hours these days, however We under no circumstances uncovered any attention-grabbing content similar to your own property. It can be attractive benefit more than enough for me personally.. how to lose weight naturally In my opinion, in the event many internet marketers plus writers manufactured exceptional content when you do, the world wide web would be a great deal more useful than ever.

  96. 18 agosto 2014 alle 16:54

    It’s actually a great and helpful piece of information. I am satisfied that you just shared this useful information with us.
    Please stay us up to date like this. Thank you for sharing.

  97. 20 agosto 2014 alle 03:00

    Woah that website is definitely wonderful i love understanding your posts. Remain on the fantastic art! You’re sure, many people are seeking rounded because of this info, you’ll be able to encourage them to tremendously.

  98. 21 agosto 2014 alle 16:55

    Magnificent site. Plenty of useful information here.

    I am sending it to a few friends ans also sharing in delicious.
    And obviously, thank you to your effort!

  99. 21 agosto 2014 alle 19:00

    It’s an amazing piece of writing in favor of all the web people; they
    will get benefit from it I am sure.

  100. 25 agosto 2014 alle 04:40

    Great blog here! Also your website loads up fast!
    What host are you using? Can I get your affiliate link to your host?
    I wish my website loaded up as fast as yours lol

  101. 31 agosto 2014 alle 08:39

    Right here is the right website for everyone who wants to find out about this topic.

    You understand so much its almost tough to argue with you (not that I personally will
    need to…HaHa). You definitely put a brand new spin on a topic that has been discussed for many years.

    Excellent stuff, just great!

  102. 31 agosto 2014 alle 15:20

    I just like the valuable information you supply for your articles.
    I’ll bookmark your blog and take a look at again right here regularly.
    I am reasonably sure I’ll be informed many new stuff proper here!
    Best of luck for the next!

  103. 2 settembre 2014 alle 04:19

    Hi there all, here every person is shareing such know-how, therefore it’s good to
    read this website, and I used to paay a visit this weblog
    everyday.

  104. 3 settembre 2014 alle 19:38

    Hi there this is somewhat of off topic but I was wanting to know if blogs use WYSIWYG editors or if you have to manually code with HTML.
    I’m starting a blopg soon but have no coding knowledge so I wanted tto get adcice
    from someone wwith experience. Any help would be enormously appreciated!

  105. 5 settembre 2014 alle 13:41

    Great post. I was checking continuously this blog and I’m impressed!
    Very helpful information particularly the laqst section :
    ) Icare for such information much. I was looking for
    this particular info for a very lengthy time. Thank you and best of luck.

  106. 9 settembre 2014 alle 20:12

    Thanks to my father who shared with me on the topic of this webpage,
    this web site is actually remarkable.

  107. 12 settembre 2014 alle 13:47

    Howdy very cool website! Male. Gorgeous. Astounding. Let me bookmark your web site as well as use the bottles also? I will be happy to try to find several useful details the following inside the post, we’d like grow much more practices for this value, many thanks for revealing.

  108. 14 settembre 2014 alle 17:33

    Thanks , I’ve just been searching for information about this subject for a long time and yours is the greatest I’ve came upon till now.
    But, what in regards to the conclusion? Are you positive in regards to the supply?

  109. 14 settembre 2014 alle 19:51

    Hi colleagues, nice paragraph and fastidious arguments commented
    here, I am genuinely enjoying by these.

  110. 15 settembre 2014 alle 00:55

    Hello, Neat article. You will find there’s problem with your blog with traveler, might test this particular? IE nonetheless will be the sector fundamental along with a great part of individuals will leave out of excellent publishing just for this problem.. Bacteria Of The Colon

  111. 16 settembre 2014 alle 18:45

    Hey! I know this is kinda off topic nevertheless I’d figured I’d
    ask. Would you be interested in trading links or maybe
    guest authoring a blog article or vice-versa?
    My site addresses a lot of the same subjects as yours
    and I believe we could greatly benefit from each other.
    If you might be interested feel free to shoot me an email.
    I look forward to hearing from you! Superb blog by the
    way!

  112. 17 settembre 2014 alle 13:49

    Superb post however , I was wanting to know if you could write a litte more on this topic?

    I’d be very thankful if you could elaborate a little bit further.
    Appreciate it!

  113. Ricky
    19 settembre 2014 alle 04:27

    Excellent write-up. I certainly appreciate this site. Thanks!

  114. 20 settembre 2014 alle 05:49

    Use pay for traffic to earn a lot more from your
    own programs.

  115. 21 settembre 2014 alle 01:05

    Thank you a bunch with regard to discussing this particular operating folks you truly determine what that you are communicating approximately! Book-marked.. how to clean out your colon home remedy Nicely furthermore take a look at my website Equates to). We can easily have got a weblink exchange set up between people

  116. 21 settembre 2014 alle 07:34

    Have you ever thought about creating an ebook or guest authoring on other sites?
    I have a blog based on the same ideas you discuss and would love
    to have you share some stories/information. I know my
    audience would appreciate your work. If you’re even remotely interested, feel free to send
    me an e mail.

  117. 22 settembre 2014 alle 22:25

    Have you ever thought about adding a little bit more
    than just your articles? I mean, what you say is valuable and all.

    But think of if you added some great pictures or video clips to
    give your posts more, “pop”! Your content is excellent but with pics and video clips, this website could definitely be one of the greatest in its field.
    Terrific blog!

  118. 23 settembre 2014 alle 01:30

    I like reading an article that will make men and women think.
    Also, many thanks for allowing for me to comment!

  119. 23 settembre 2014 alle 05:49

    Very nice blog post. I certainly appreciate this website.
    Stick with it!

  120. 23 settembre 2014 alle 11:44

    During the period of the 14-year research period,

  121. 26 settembre 2014 alle 14:24

    Heya i’m for the first time here. I found this board and I find It really useful & it helped me out much.
    I hope to give something back and help others like you aided me.

  122. 26 settembre 2014 alle 22:47

    Heya! I just wanted to ask if you ever have any issues with hackers?

    My last blog (wordpress) was hacked and I ended up losing a few months of
    hard work due to no backup. Do you have any solutions
    to prevent hackers?

  123. 27 settembre 2014 alle 03:26

    If you want to know the crystal clear details it is better to view just about any
    online store web sites explaining the actual product or service information using elements.
    There are various surgical methods to combat obesity. Indeed Adiphene weight reduction pill is the
    answer for those who always goes on food regimen however can’t endure the meals carving hunger and the irritability gave
    rise by dieting.

  124. 29 settembre 2014 alle 01:10

    So why is being overweight such a direct link to diabetes.
    Adiphene the new weight loss formula is now available with
    the power of 11 different fat burners to boost weight loss.
    Assuming that you aren’t a super-taught individual, you will have some major snags adding on control over your zealous urges towards consuming
    distinctive sustenances.

  125. 29 settembre 2014 alle 06:55

    What i don’t undeerstood is actually how you aree not reallly much more smartly-liked thjan you might be now.
    You’re very intelligent. You realize thus significantly witth
    regards to this matter, made me in my view believe it
    from sso many various angles. Its like meen and women aren’t fascinated until it is one thing to do with Lady gaga!
    Your own stucfs excellent. At all times deal with it up!

  126. 1 ottobre 2014 alle 10:32

    Furthermore, at the request of primary physicians at over 45 clinical centres throughout the
    USA, Canada,

  127. 2 ottobre 2014 alle 07:17

    Hi there! I understand this is kind of off-topic but I had to ask.
    Does running a well-established blog like yours require a massive amount work?

    I’m brand new to operating a blog but I do write in my
    journal on a daily basis. I’d like to start a blog so I can share my
    own experience and views online. Please let me know if you have any suggestions or tips
    for brand new aspiring blog owners. Appreciate it!

  128. 2 ottobre 2014 alle 10:08

    Hello! I could have sworn I’ve been to this site before but after browsing
    through some of the post I realized it’s new to me.
    Anyways, I’m definitely glad I found it and I’ll be book-marking
    and checking back often!

  129. 4 ottobre 2014 alle 05:50

    I’ll immediately snatch your rss feed as I can’t
    to find your e-mail subscription link or e-newsletter service.
    Do you’ve any? Please let me understand in order that I
    could subscribe. Thanks.

  130. 4 ottobre 2014 alle 06:50

    So why is being overweight such a direct link to
    diabetes. There are various surgical methods to combat obesity.
    Adiphene Weight Loss Supplements Offers a Unique 25% Discount
    n select package fr Online B Worldwide If the online critiques
    are something to go by, Adiphene is an efficient weight-loss option.

  131. 4 ottobre 2014 alle 15:54

    wonderful points altogether, you just won a new reader.
    What might you recommend about your post that you just made a few days ago?

    Any sure?

  132. 5 ottobre 2014 alle 01:14

    Don’t let fat cost-free or perhaps gentle meals trick anyone; them usually comprise copious amounts connected
    with one more unhealthy element. Individuals who have underlying medical condition should also consult a physician before
    taking this diet pill. The science behind Adiphene consists of 12
    of probably the most power fat preventing ingredients
    known.

  133. 5 ottobre 2014 alle 04:34

    Greetings I am so happy I found your site, I really found you by error, while
    I was looking on Aol for something else, Anyhow
    I am here now and would just like to say thank you for a
    marvelous post and a all round entertaining blog (I also love the
    theme/design), I don’t have time to go through it all at the moment
    but I have saved it and also added your RSS feeds, so when I
    have time I will be back to read a great deal more, Please do keep up the fantastic work.

  134. 7 ottobre 2014 alle 18:07

    Write more, thats all I have to say. Literally, it seems as though you
    relied on the video to make your point. You definitely know what youre talking about, why waste your intelligence on just posting videos to your blog when you could
    be giving us something informative to read?

  135. 8 ottobre 2014 alle 03:08

    I like looking through an article that can make people think.
    Also, thanks for allowing for me to comment!

  136. 8 ottobre 2014 alle 03:27

    It reduces fats and carb absorption, reduces urge for food, stimulates the metabolism
    promoting fats burning and offers you extra vitality.
    It’s conceivable to accomplish this objective the conventional path moreover through an equalized eating methodology and exercise.
    There is a section to discuss the biggest loser show, specific diets,
    and much more.

  137. 9 ottobre 2014 alle 06:03

    Hey There. I found your blog using msn. This is an extremely well written article.

    I will make sure to bookmark it and return to read more of your useful information. Thanks for the post.
    I will definitely return.

  138. 10 ottobre 2014 alle 20:32

    WOW just what I was looking for. Came here by searching for effective diet

  139. 12 ottobre 2014 alle 07:58

    Thanks for sharing your thoughts on homemade
    acne remedies that work. Regards

  140. 12 ottobre 2014 alle 16:57

    Everything said was very reasonable. But, what about this?
    what if you added a little content? I ain’t suggesting your content is not good., but suppose you added a headline that grabbed a person’s attention? I mean Come funziona il diabete | La Strana Malattia
    iis kinda plain. You could glance at Yahoo’s front page and see how thhey write news titles to get
    people interested. You might try adding a video or a picture or two to grab people interested about what you’ve written. Just my opinion, it
    could make your blog a little bit more interesting.

  141. 16 ottobre 2014 alle 13:26

    Thank you for any other informative site. Where else may I get that type of
    information written in such an ideal manner? I’ve a
    project that I’m simply now running on, and I have been on the look out for such info.

  142. 25 ottobre 2014 alle 18:18

    That is a really good tip especially to those fresh to the blogosphere.

    Brief but very precise info… Appreciate
    your sharing this one. A must read article!

  143. 17 novembre 2014 alle 22:08

    If you want to know the crystal clear details it is better to view just about any online store web sites
    explaining the actual product or service information using elements.
    Individuals who have underlying medical condition should also consult
    a physician before taking this diet pill. There is a section to discuss the biggest loser show, specific diets,
    and much more.

  144. 1 dicembre 2014 alle 20:32

    Hi there, You have done a fantastic job.
    I’ll definitely digg it and personally suggest to my friends.
    I’m confident they’ll be benefited from this website.

  145. 11 gennaio 2015 alle 20:40

    Hello, the whole thing is going sound here and ofcourse every one is sharing data,
    that’s in fact fine, keep up writing.

  146. 17 gennaio 2015 alle 22:08

    I was recommended this blog by my cousin. I am no longer sure
    whether or not this post is written by him as no one else recognise such specified approximately my trouble.
    You’re wonderful! Thank you!

  147. 29 gennaio 2015 alle 16:52

    I believe this is one of the most vital information for me.
    And i’m satisfied studying your article. However should statement
    on some normal things, The website style is great, the articles is truly nice : D.
    Just right activity, cheers

  148. 13 marzo 2015 alle 12:01

    Don’t let fat cost-free or perhaps gentle meals trick anyone; them usually comprise copious amounts
    connected with one more unhealthy element. Adiphene is the
    newest and fastest weight reduction supplement in market.
    Different studies have demonstrated the profits of Ginseng Panax Root Extract.

  149. 24 dicembre 2015 alle 22:54

    Greetings! I’ve been reading your website for
    a while now and finally got the bravery to go ahead and give you
    a shout out from Huffman Texas! Just wanted to say keep up the excellent work!

  150. 22 agosto 2016 alle 02:37

    審査の基準は金融機関によって違いはありますが、借り入れの額が50万以下だと収入の証明も必要ないほどですから借入は何処でも簡単です。しかし借入額が高額になったとき、銀行系の即日融資カードローンは、利息が低いため審査は非常に厳しいといわれています。WEBを見ると大変楽に手続きができて、すぐに融資を受けられるようなCMがされていますが、実際のところ銀行カードローンの審査はかなり通過しづらいものです。とはいえ低い利息を得るには難しくてもチャレンジすべきことです。

  151. 29 dicembre 2016 alle 10:11

    Wow, superb weblog structure! How lengthy have you been blogging for?
    you made running a blog look easy. The full glance of your web site is magnificent, as smartly as the content material!

  152. 1 gennaio 2017 alle 17:22

    Hi, all is going fine here and ofcourse every one
    is sharing facts, that’s genuinely good, keep up writing.

  153. 24 febbraio 2017 alle 10:57

    Nice post. I learn something totally new and challenging on blogs I stumbleupon every
    day. It will always be helpful to read articles from other
    writers and practice something from their websites.

  154. 16 marzo 2017 alle 00:39

    Helⅼo there! Dο ʏou uѕe Twitter? I’d liкe to follow үoᥙ іf that
    would bе ok. I’m bsolutely enjoying yߋur blog аnd ⅼⲟok forward tо nеԝ updates.

  155. Patrickalups
    27 aprile 2017 alle 08:09

    Shot book ceremony as like http://www.essayonlineshop.com/ is an scholastic letter medium that is designed to eschew you not on with your abstract tasks. They provide labourers with the following assignments: college and high public school essays, research and incumbency papers, idea

    proposals and capstone projects, book and talking picture reviews, article critiques and impractical tutorials, idiolect and launch support, CVs, mask

    letters, resumes and other job effort assistance, lab reports, scientific studies, etc. Anything you can think of, we can do it. Their ambition is

    to yield you scale superiority scribble literary works stop to set right your total results at seminary or university.

  1. 30 aprile 2014 alle 02:40
  2. 3 maggio 2014 alle 15:57
  3. 21 maggio 2014 alle 21:45
  4. 24 maggio 2014 alle 18:33
  5. 7 giugno 2014 alle 06:58
  6. 12 giugno 2014 alle 23:39
  7. 21 giugno 2014 alle 17:37
  8. 22 giugno 2014 alle 03:01
  9. 23 giugno 2014 alle 09:28
  10. 23 giugno 2014 alle 09:49
  11. 23 giugno 2014 alle 15:31
  12. 23 giugno 2014 alle 16:12
  13. 24 giugno 2014 alle 00:12
  14. 24 giugno 2014 alle 05:23
  15. 24 giugno 2014 alle 05:28
  16. 24 giugno 2014 alle 06:11
  17. 25 giugno 2014 alle 05:21
  18. 25 giugno 2014 alle 06:38
  19. 25 giugno 2014 alle 06:52
  20. 25 giugno 2014 alle 07:03
  21. 25 giugno 2014 alle 07:42
  22. 27 giugno 2014 alle 09:14
  23. 29 giugno 2014 alle 01:39
  24. 30 giugno 2014 alle 01:36
  25. 30 giugno 2014 alle 10:39
  26. 8 luglio 2014 alle 04:45
  27. 8 luglio 2014 alle 12:21
  28. 10 luglio 2014 alle 12:16
  29. 11 luglio 2014 alle 08:42
  30. 19 luglio 2014 alle 08:35
  31. 21 luglio 2014 alle 03:15
  32. 27 luglio 2014 alle 06:15
  33. 25 agosto 2014 alle 08:14
  34. 16 settembre 2014 alle 18:26
  35. 26 settembre 2014 alle 15:21
  36. 16 gennaio 2015 alle 01:15
  37. 12 febbraio 2015 alle 06:14
  38. 1 agosto 2015 alle 09:58
  39. 27 marzo 2017 alle 17:46

Rispondi

Inserisci i tuoi dati qui sotto o clicca su un'icona per effettuare l'accesso:

Logo WordPress.com

Stai commentando usando il tuo account WordPress.com. Chiudi sessione / Modifica )

Foto Twitter

Stai commentando usando il tuo account Twitter. Chiudi sessione / Modifica )

Foto di Facebook

Stai commentando usando il tuo account Facebook. Chiudi sessione / Modifica )

Google+ photo

Stai commentando usando il tuo account Google+. Chiudi sessione / Modifica )

Connessione a %s...

%d blogger hanno fatto clic su Mi Piace per questo: